Dataset Information


Is the adipofascial flap the key to regenerative surgery?



"Form and function restoration" is the ultimate goal of reconstructive surgery, which is oriented toward regeneration rather than reparation. Recently, research in reconstructive surgery has focused on the regenerative potential of the adipose tissue. The aim of the study is to illustrate the surgical methods and show the functional and aesthetic results achieved by the reconstruction of finger soft-tissue defects using homodigital dorsal adipofascial reverse flap (HDARF).

Materials and methods

A total of 63 cases (45 acute and 18 elective) were included between September 2010 and August 2016. In each case, we preliminarily performed surgical debridement and then harvested an adipofascial flap from the back of the finger. Nine injured thumbs that were repaired with the flap as emergency cases were also included. The average age of the patients was 46 (range: 4-69) years.


All flaps survived without any complications during the 24-month follow-up. Good nail regrowth through the flap and full regeneration were observed in approximately all cases. Sensitivity tests and histological analysis of biopsy samples of the regenerated fingers confirmed full regeneration of the epidermis, dermis, cutaneous adnexa, and nerves. All the patients were satisfied with the hand functionality and aesthetic appearance.


The HDARF represents a very useful alternative for the reconstruction of nailbed crushes, achieving regeneration of injured segments in deformities caused by trauma or infection.

PROVIDER: S-EPMC7061596 | BioStudies |

REPOSITORIES: biostudies

Similar Datasets

| S-EPMC9308155 | BioStudies
| S-EPMC7544165 | BioStudies
| S-EPMC7760566 | BioStudies
| S-EPMC8554457 | BioStudies
| S-EPMC8677592 | BioStudies
| S-EPMC6370060 | BioStudies
2009-01-01 | S-EPMC3052652 | BioStudies
| S-EPMC6754012 | BioStudies
| S-EPMC7544277 | BioStudies
2010-01-01 | S-EPMC3324247 | BioStudies