Dataset Information


Perioperative Hyperoxyphobia: Justified or Not? Benefits and Harms of Hyperoxia during Surgery.

ABSTRACT: The use of an inspiratory oxygen fraction of 0.80 during surgery is a topic of ongoing debate. Opponents claim that increased oxidative stress, atelectasis, and impaired oxygen delivery due to hyperoxic vasoconstriction are detrimental. Proponents point to the beneficial effects on the incidence of surgical site infections and postoperative nausea and vomiting. Also, hyperoxygenation is thought to extend the safety margin in case of acute intraoperative emergencies. This review provides a comprehensive risk-benefit analysis for the use of perioperative hyperoxia in noncritically ill adults based on clinical evidence and supported by physiological deduction where needed. Data from the field of hyperbaric medicine, as a model of extreme hyperoxygenation, are extrapolated to the perioperative setting. We ultimately conclude that current evidence is in favour of hyperoxia in noncritically ill intubated adult surgical patients.


PROVIDER: S-EPMC7141263 | BioStudies | 2020-01-01

SECONDARY ACCESSION(S): 10.28920/dhm47.2.131-132

REPOSITORIES: biostudies

Similar Datasets

2019-01-01 | S-EPMC6610986 | BioStudies
2014-01-01 | S-EPMC4223034 | BioStudies
2019-01-01 | S-EPMC6727888 | BioStudies
2019-01-01 | S-EPMC6492293 | BioStudies
1000-01-01 | S-EPMC2738805 | BioStudies
2014-01-01 | S-EPMC4298955 | BioStudies
2018-01-01 | S-EPMC5770109 | BioStudies
2019-01-01 | S-EPMC6390560 | BioStudies
2020-01-01 | S-EPMC7140073 | BioStudies
2017-01-01 | S-EPMC5364633 | BioStudies