Unknown

Dataset Information

0

Medications and in-hospital outcomes in infants born at 22-24 weeks of gestation.


ABSTRACT: OBJECTIVE:To evaluate the most commonly used medications and in-hospital morbidities and mortality in infants born 22-24 weeks of gestation. STUDY DESIGN:Multicenter retrospective cohort study of infants born 22-24 weeks of gestation (2006-2016), without major congenital anomalies and with available medication data obtained from neonatal intensive care units managed by the Pediatrix Medical Group. RESULTS:This study included 7578 infants from 195 sites. Median (25th, 75th percentile): birthweight was 610?g (540, 680); the number of distinct medications used was 13 (8, 18); and different antimicrobial exposure was 4 (2, 5). The most common morbidities were BPD (41%) and grade III or IV IVH (20%), and overall survival varied from 46% (2006) to 57% (2016). CONCLUSIONS:A large number of medications were used in periviable infants. There was a high prevalence of in-hospital morbidities, and survival of this population increased over the study period.

SUBMITTER: Puia-Dumitrescu M 

PROVIDER: S-EPMC7293630 | BioStudies | 2020-01-01

REPOSITORIES: biostudies

Similar Datasets

2019-01-01 | S-EPMC6335180 | BioStudies
2017-01-01 | S-EPMC5304177 | BioStudies
1000-01-01 | S-EPMC4177255 | BioStudies
1000-01-01 | S-EPMC5966853 | BioStudies
2017-01-01 | S-EPMC5496967 | BioStudies
1000-01-01 | S-EPMC5630631 | BioStudies
2020-01-01 | S-EPMC7355268 | BioStudies
2016-01-01 | S-EPMC4894251 | BioStudies
2017-01-01 | S-EPMC5644703 | BioStudies
2015-01-01 | S-EPMC4787615 | BioStudies