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ATP-sensitive potassium channels gene polymorphism rs1799858 affects the risk of macro-/micro-vascular arteriosclerotic event in patients with increased low-density lipoprotein cholesterol levels.


ABSTRACT: BACKGROUND:Plasma concentration of low-density lipoprotein cholesterol (LDL-C) is causally related to the risk of arteriosclerotic events. Whether ATP-sensitive potassium channels (KATP) genetic variants predict increased LDL-C concentration (?1.8?mmol/L) and risk of macro-/micro-vascular arteriosclerotic event remain elusive. METHODS:A total of 320 subjects with increased LDL-C concentration (?1.8?mmol/L) and 320 counterpart subjects (

SUBMITTER: Liu C 

PROVIDER: S-EPMC7313205 | BioStudies | 2020-01-01

SECONDARY ACCESSION(S): NC_000011.10

REPOSITORIES: biostudies

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