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Contact, high-resolution spatial diffuse reflectance imaging system for skin condition diagnosis: a first-in-human clinical trial.


ABSTRACT:

Significance

Oxygenation is one of the skin tissue physiological properties to follow for patient care management. Furthermore, long-term monitoring of such parameters is needed at the patient bed as well as outside the hospital. Diffuse reflectance spectroscopy has been widely used for this purpose.

Aim

The aim of the study is to propose a low-cost system for the long-term measurement of skin physiological parameters in contact.

Approach

We have developed a low-cost, wearable, CMOS-based device. We propose an original method for processing diffuse reflectance data to calculate the tissue oxygen saturation (StO2).

Results

We tested the device for the assessment of tissue oxygenation during a first-in-human clinical trial that took place at the Grenoble University Hospital France.

Conclusions

The results of this clinical trial show a good accordance between our sensor and commercial devices used a reference.

PROVIDER: S-EPMC7846121 | BioStudies |

REPOSITORIES: biostudies

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