Models

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FGF pathway of Drosophila Signalling Pathways


ABSTRACT: Fig 3B from the following paper\r\nLogical modelling of Drosophila signalling pathways. Mbodj A, Junion G, Brun C, Furlong EE, Thieffry D. Mol Biosyst. 2013 Sep;9(9):2248-58. doi:10.1039/c3mb70187e

SUBMITTER: Tomas Helikar 

PROVIDER: 3510 | Cell Collective |

REPOSITORIES: Cell Collective

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Logical modelling of Drosophila signalling pathways.

Mbodj Abibatou A   Junion Guillaume G   Brun Christine C   Furlong Eileen E M EE   Thieffry Denis D  

Molecular bioSystems 20130901 9


A limited number of signalling pathways are involved in the specification of cell fate during the development of all animals. Several of these pathways were originally identified in Drosophila. To clarify their roles, and possible cross-talk, we have built a logical model for the nine key signalling pathways recurrently used in metazoan development. In each case, we considered the associated ligands, receptors, signal transducers, modulators, and transcription factors reported in the literature.  ...[more]

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