The Genome and Transcriptome of Fibrolamellar Hepatocellular Carcinoma

ABSTRACT:

Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare liver tumor primarily affecting adolescents and young adults. Little is known of the molecular pathogenesis. To characterize the disease we performed RNA sequencing and whole genome sequencing on FL-HCC tumors and adjacent normal tissue. The results demonstrate few consistent differences on the chromosomal level and many hundreds of alterations in the expression of RNA transcripts.

PROVIDER: phs000709 | dbGaP |

SECONDARY ACCESSION(S): PRJNA236539PRJNA236540

REPOSITORIES: dbGaP