Genomics

Dataset Information

27

Transcriptome sequencing of Pediatric Neuroblastoma


ABSTRACT: "Neuroblastoma is the most common extra-cranial solid tumor in children. It represents 8% to 10% of all childhood cancers. Stage 4 Neuroblastoma is characterized by its clinical heterogeneous outcome. The special category, stage 4S tumors (2-5% of all NB) are chemo-sensitive, and the patients show spontaneous regression. On the other hand, MYCN amplification (25-30% of all NB) is associated with poor outcome of neuroblastoma, thus we further categorize stage 4 neuroblastoma into MYCN non-amplified and MYCN amplified group. Here we use transcriptome sequencing to characterize the transcriptome in 29 stage 4 Neuroblastoma samples."

PROVIDER: phs000868 | dbGaP |

SECONDARY ACCESSION(S): PRJNA275174PRJNA275173

REPOSITORIES: dbGaP

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