Genomics

Dataset Information

136

TCR Repertoire of CD4+ T cells in Human Lymph Nodes


ABSTRACT: The TCR repertoire of CD4+ T cells in human lymph nodes is a case-based analysis of the TCR repertoire of CD4+ T cells in human lymph nodes. The study aims to determine how HIV infection alters the repertoire complexity of follicular helper T cells (TFH) in relationship to other T cell subsets in the lymphoid compartment. This study performs TCR repertoire sequencing using Molecular Identifier Clustering-based Immune Repertoire Sequencing (MIDCIRS). We found TFH cells become clonally expanded and convergently selected in LNs from patients with chronic HIV infection.

PROVIDER: phs001548 | dbGaP |

REPOSITORIES: dbGaP

Similar Datasets

| phs001849 | dbGaP
| PRJNA434344 | ENA
| PRJNA434343 | ENA
2016-12-21 | E-MTAB-4214 | ArrayExpress
| GSE71162 | GEO
2014-10-07 | E-GEOD-62104 | ArrayExpress
2005-01-01 | MODEL1006230081 | BioModels
2005-01-01 | MODEL1006230033 | BioModels
2019-03-29 | PXD012052 | Pride
2016-04-13 | E-MTAB-4619 | ArrayExpress