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Analysis of patients’ survival status after super-minimally invasive surgery versus organ resection for colorectal tumors

ABSTRACT: Interventions: Super Minimally Invasive Surgery Group:None;Organ removal type surgery group:None Primary outcome(s): Quality of life;Mental state Study Design: Cohort study

DISEASE(S): Colorectal Tumors

PROVIDER: 106792 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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Minimally Invasive Surgery (MIS) Database for the Purpose of Research

Project description:The Minimally Invasive Surgery Team (MIST) are establishing a separate research database to find out more about patient’s undergoing minimally invasive surgery (laparoscopic , open and robot assisted) procedures at UCSD. The hope is that collection of this information will give physicians a better knowledge and understanding of the benefits of minimally invasive surgery and possibly assist physicians to better manage future patients.

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Array-based genome-wide transcriptome analysis of Minimally invasive follicular thyroid carcinomas

Project description:Minimally invasive follicular thyroid carcinoma (MI-FTC) is characterized by limited capsular and/or vascular invasion with good long-term outcomes. However, some cases of MI-FTC show a poor prognosis because of severe distant metastasis. Nonetheless, no method has been established for predicting the prognosis of MI-FTC. This study was conducted to identify novel prognostic factors for metastatic MI-FTC by use of the formalin-fixed paraffin-embedded (FFPE) specimens of this carcinoma.

2018-10-01 | GSE111455 | GEO

Human lung minimally invasive adenocarcinoma (MIA): lepidic growth (LG) cancer cell pool vs. micro-invasion (MI) cancer cell pool

Project description:Transcriptional profiling of human lung minimally invasive adenocarcinoma cells comparing control lepidic growth (LG) cell pool with micro-invasion (MI) cell pool.

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Mechanical Ileus in the Era of Minimally Invasive Colorectal Surgery

Project description:The present study was to investigate if the incidence, patterns and surgical outcomes of mechanical ileus have changed in the era of minimally invasive surgery (MIS).

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Human lung minimally invasive adenocarcinoma (MIA): lepidic growth (LG) cancer cell pool vs. micro-invasion (MI) cancer cell pool

Project description:Transcriptional profiling of human lung minimally invasive adenocarcinoma cells comparing control lepidic growth (LG) cell pool with micro-invasion (MI) cell pool. Two-condition experiment, LG vs. MI cell pools. Biological replicates: 1 control LG cancer cell, 1 MI cancer cell in an individual MIA tumor. One replicate per array.

2012-01-02 | E-GEOD-30663 | biostudies-arrayexpress

Global evolution of the tumor microenvironment associated with progression from preinvasive/minimally invasive to invasive human lung adenocarcinoma

Project description:To investigate changes in the tumor microenvironment (TME) during lung cancer progression, we interrogate tumors from two computer tomography (CT) defined groups. Pure non-solid (pNS) CT density nodules contain preinvasive/minimally invasive cancers and solid density nodules invasive cancers. Profiling data reveal a dynamic interaction between the tumor and its TME throughout progression. Alterations in genes regulating the extracellular matrix and genes regulating fibroblasts are central at the preinvasive state. T cell-mediated immune suppression is initiated in preinvasive nodules and sustained with rising intensity through progression to invasive tumors. Reduced T cell infiltration of the cancer cell nests is more frequently associated with preinvasive cancers, possibly until tumor evolution leads to a durable, viable invasive phenotype accompanied by more varied and robust immune suppression. Upregulation of immune checkpoints occurs only in the invasive nodules. Throughout progression an effector immune response is present but is effectively thwarted by the immune-suppressive elements.

2022-04-10 | GSE193725 | GEO

Development of a novel minimally invasive sampling and analysis technique for bioarchaeological proteomics

Project description:Here we present the development of a novel minimally invasive sample preparation technique for application in the mass spectrometric analysis of bioarchaeological materials. The extraction protocol was developed by applying commercially available, dermatology grade skin sampling strips to modern skin surfaces as a surrogate, and then applied to cranial and bone fragments belonging to a 26th Dynasty Egyptian mummified individual from the coffin of a woman named Mer-Neith-it-es. Extracted proteins were subjected to electrophoretic separation and proteolytic digestion, resulting in peptides that were separated, fragmented and identified using nanoflow liquid chromatography - high resolution tandem mass spectrometry. We have identified a number of ancient brain and intracellular proteins on the surfaces of the various cranial and bone fragments, without causing any significant damage to these valuable remains.

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Rational biomarker development for the early and minimally invasive monitoring of AML

Project description:Rational biomarker development for the early and minimally invasive monitoring of AML

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Array-based genome-wide transcriptome analysis of Minimally invasive follicular thyroid carcinomas

Project description:Array-based genome-wide transcriptome analysis of Minimally invasive follicular thyroid carcinomas

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Species identification of ivory and bone museum objects using minimally invasive proteomics

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