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Study of AMN107 With Imatinib in Gastrointestinal Stromal Tumors (GIST)

ABSTRACT: This study is an open-label, multicenter, Phase I dose-escalation study of the combination of AMN107 and imatinib (STI571) in patients with imatinib-resistant GIST. This study is designed to determine the Phase II dose of AMN107 and imatinib when administered together in patients with imatinib-resistant GIST, and to characterize the safety, tolerability and pharmacokinetic (PK) profile of this combination.

DISEASE(S): Treatment Of Imatinib Resistant Gastro-intestinal Stromal Tumors (gist).,Gastrointestinal Stromal Tumors

PROVIDER: 2014616 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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