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Tumor Necrosis Factor Decreases Vitamin D Dependant Calcium Absorption

ABSTRACT: This study is a pilot study to determine whether patients with TNFα excess have decreased calcium absorption in response to calcitriol (1,25-dihydroxyvitamin D, the active form of vitamin D) compared to normal controls. This initial pilot study is being done to determine if it is feasible to conduct a study where TNFα could be blocked (e.g., by anti-TNFα therapy such as Enbrel or Remicade) to improve vitamin D dependant calcium absorption and thus bone health.

DISEASE(S): Crohn's Disease,Rheumatoid Arthritis,Crohn Disease,Necrosis

PROVIDER: 2036554 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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