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Lenalidomide After Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancers


ABSTRACT: This phase I clinical trial is studying the side effects and the best dose of lenalidomide after donor bone marrow transplant in treating patients with high-risk hematologic cancer. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing.

DISEASE(S): Adult Acute Promyelocytic Leukemia With Pml-rara,Adult Grade Iii Lymphomatoid Granulomatosis,Lymphoma, Large-cell, Immunoblastic,Mature T-cell And Nk-cell Non-hodgkin Lymphoma,Lymphoproliferative Disorders,Recurrent Grade 1 Follicular Lymphoma,Refractory Hairy Cell Leukemia,Sezary Syndrome,T-cell Large Granular Lymphocyte Leukemia,Adult Nasal Type Extranodal Nk/t-cell Lymphoma,Splenic Marginal Zone Lymphoma,Leukemia, Hairy Cell,Adult Acute Myeloid Leukemia With T(9;11)(p22.3;q23.3); Mllt3-kmt2a,Refractory Chronic Lymphocytic Leukemia,Mycosis Fungoides,Lymphoma, Mantle-cell,Leukemia-lymphoma, Adult T-cell,Alkylating Agent-related Acute Myeloid Leukemia,Adult Acute Myeloid Leukemia In Remission,Richter Syndrome,Recurrent Primary Cutaneous T-cell Non-hodgkin Lymphoma,Recurrent Adult Burkitt Lymphoma,Leukemia, T-cell,Lymphomatoid Granulomatosis,Lymphoma, T-cell, Peripheral,Adult Acute Myeloid Leukemia With T(8;21); (q22; Q22.1); Runx1-runx1t1,Lymphoma, Extranodal Nk-t-cell,Plasmablastic Lymphoma,Lymphoma, B-cell, Marginal Zone,Burkitt Lymphoma,Extranodal Marginal Zone Lymphoma Of Mucosa-associated Lymphoid Tissue,Post-transplant Lymphoproliferative Disorder,Recurrent Small Lymphocytic Lymphoma,Recurrent Mycosis Fungoides And Sezary Syndrome,Lymphoma, T-cell, Cutaneous,Recurrent Marginal Zone Lymphoma,Recurrent Adult Grade Iii Lymphomatoid Granulomatosis,Waldenstrom Macroglobulinemia,Lymphoma, Follicular,Recurrent Adult Immunoblastic Lymphoma,Small Intestinal Lymphoma,Leukemia, Lymphocytic, Chronic, B-cell,Intraocular Lymphoma,Recurrent Mantle Cell Lymphoma,Recurrent Grade 3 Follicular Lymphoma,Leukemia,Mycoses,Angioimmunoblastic T-cell Lymphoma,Recurrent Adult Lymphoblastic Lymphoma,Leukemia, Myeloid, Acute,Leukemia, Large Granular Lymphocytic,Testicular Lymphoma,Lymphomatous Involvement Of Non-cutaneous Extranodal Site,Nodal Marginal Zone Lymphoma,Lymphoma, Large-cell, Anaplastic,Leukemia, Promyelocytic, Acute,Lymphoma, T-cell,Primary Cutaneous B-cell Non-hodgkin Lymphoma,Hepatosplenic T-cell Lymphoma,Leukemia, Myeloid,Prolymphocytic Leukemia,Immunoblastic Lymphadenopathy,Leukemia, Prolymphocytic,Precursor Cell Lymphoblastic Leukemia-lymphoma,Lymphoma,Recurrent Non-hodgkin Lymphoma,Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); Cbfb-myh11,Anaplastic Large Cell Lymphoma,Recurrent Grade 2 Follicular Lymphoma,Recurrent Adult T-cell Leukemia/lymphoma,Adult Acute Myeloid Leukemia With T(16;16)(p13.1;q22); Cbfb-myh11,Lymphoma, Non-hodgkin,Lymphoma, B-cell

PROVIDER: 2099113 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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