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Efficacy and Safety of Simtuzumab (SIM) With FOLFIRI as Second Line Treatment in Colorectal Adenocarcinoma

ABSTRACT: The primary objective of this study is to compare the additive efficacy of SIM versus placebo in combination with leucovorin (folinic acid), irinotecan, and fluorouracil (FOLFIRI) as measured by improvement in progression-free survival (PFS) in participants with metastatic KRAS mutant colorectal adenocarcinoma who have progressed following a first-line oxaliplatin- and fluoropyrimidine-containing regimen.

DISEASE(S): Adenocarcinoma,Colorectal Adenocarcinoma,Adenocarcinoma Colo-rettale Metastatico Kras Mutante,Colorectal Cancer,Metastatic Kras Mutant Colorectal Adenocarcinoma,Colorectal Neoplasms,Neoplasms Benign, Malignant And Unspecified (incl Cysts And Polyps)

PROVIDER: 2116262 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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