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A Study to Investigate Efficacy and Safety of Cobimetinib Plus Atezolizumab and Atezolizumab Monotherapy Versus Regorafenib in Participants With Metastatic Colorectal Adenocarcinoma (COTEZO IMblaze370)

ABSTRACT: This is a Phase III, multicenter, open-label, three-arm, randomized study in participants with unresectable locally advanced or metastatic colorectal cancer (CRC) who have received at least two prior regimens of cytotoxic chemotherapy for metastatic disease. The study compares regorafenib, a standard of care therapy in this setting, to cobimetinib plus atezolizumab and atezolizumab monotherapy.

DISEASE(S): Adenocarcinoma,The Patient Population Are Patients With Metastatic Or Locally Advanced Unresectable Colorectal Adenocarcinoma That Have Received At Least Two Lines Of Chemotherapy In This Setting. The Patients Must Have Received 5-fu, Oxaliplatin, And Irinotecan. Patients Who Have Received An Anti-vegf And Anti-egfr Are Eligible.,Colorectal Cancer,Colorectal Cancer Metastatic

PROVIDER: 2216377 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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