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A Study to Investigate ONCOS-102 in Combination With Durvalumab in Subjects With Advanced Peritoneal Malignancies

ABSTRACT: This is a two-part Phase 1/2 dose escalation and dose expansion study of an Adenovirus Vector (Ad5/3-D24-GMCSF), Expressing GM-CSF (GM-CSF-encoding adenovirus), ONCOS-102, in combination with anti-programmed death ligand-1 (PD-L1) antibody, durvalumab, in adult subjects with peritoneal disease who have failed prior standard chemotherapy and have histologically confirmed epithelial ovarian cancer or metastatic colorectal cancer.

DISEASE(S): Ovarian Cancer,Appendiceal Cancer,Colorectal Cancer,Appendiceal Neoplasms

PROVIDER: 2229839 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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