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A Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100)

ABSTRACT: Evaluate the safety and tolerability of sotorasib in adult subjects with KRAS p.G12C mutant advanced solid tumors. Estimate the maximum tolerated dose (MTD) and/or a recommended phase 2 dose (RP2D) in adult subjects with KRAS p.G12C mutant advanced solid tumors.

DISEASE(S): Colorectal Cancer,Non-small Cell Lung Cancer,Kras P.g12c Mutant Advanced Nsclc, Crc, And Other Solid Tumors,Kras P.g12c Mutant Advanced Solid Tumors,Neoplasms

PROVIDER: 2278745 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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