Sirolimus for Cowden Syndrome With Colon Polyposis

ABSTRACT: Colon polyposis (the presence of multiple colon polyps) is very common with Cowden syndrome, as over 60% of patients have 50 or more polyps. In a previous clinical trial, some participants had reduction in the number of colon polyps with the use of the medication sirolimus for a very short time period. This study is investigating sirolimus and its effect on the number of colon polyps in patients with Cowden syndrome and polyposis over a 1 year period.

DISEASE(S): Bannayan Zonana Syndrome,Pten Hamartoma Syndrome,Cowden Syndrome,Hamartoma Syndrome, Multiple,Pten Hamartoma Tumor Syndrome,Bannayan Syndrome,Colorectal Neoplasms,Pten Gene Mutation,Nasopharyngeal Neoplasms,Polyposis,Neoplasms,Hamartoma

PROVIDER: 2316670 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR