Browse
Submit Data
Databases
API
Help

Dataset Information

5 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Perfusion Rate Assessment by Near-infrared Fluorescence in Gastrointestinal Anastomoses

ABSTRACT: In this prospective, non-randomized cohort study, real-time intraoperative visualization using near-infrared-fluorescence by indocyanine green injection (ICG-NIRF) is performed at two to three time points during procedures of upper GI, lower GI and hepatobiliary surgery with anastomosis formation in open or laparoscopic surgery. Postoperatively, a detailed software-based assessment of each recording is performed to determine the objective ICG-NIRF perfusion rate before and after anastomosis formation, which is then correlated with the 30 day postoperative clinical outcome including occurrence of anastomotic leak.

DISEASE(S): Gastrointestinal Neoplasms,Bowel Obstruction,Adenomatous Polyposis Coli,Crohn Disease,Symptomatic Disorders Of The Gastrointestinal Tract,Neoplasms,Bowel Ischemia,Diverticulitis,Ulcerative Colitis,Stoma Ileostomy,Hepatobiliary Neoplasm,Abnormality Of The Gastrointestinal Tract,Familial Adenomatous Polyposis,Cancer Of The Gastrointestinal Tract,Pancreatic Neoplasms,Intestinal Obstruction

PROVIDER: 2363901 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

ACCESS DATA

Json Xml

Similar Datasets

Objective Perfusion Rate Assessment by Near-infrared Fluorescence in Ileal Pouch Formation and Ileal-pouch-anal Anastomosis

Project description:In this prospective, non-randomized cohort study, real-time intraoperative visualization using near-infrared-fluorescence by indocyanine green injection (ICG-NIRF) is performed at three time points during ileal pouch reconstruction. Postoperatively, a detailed software-based assessment of each pouch recording is performed to determine the objective ICG-NIRF perfusion rate, which is then correlated with the 30 day postoperative clinical outcome including occurrence of anastomotic leak of the pouch.

| 2362864 | ecrin-mdr-crc

Subjective Near-infrared Fluorescence Guidance in Perfusion Assessment of Ileal Pouch Formation and Ileal-pouch-anal Anastomosis

Project description:In this prospective, non-randomized cohort study, real-time intraoperative visualization using near-infrared-fluorescence by indocyanine green injection (ICG-NIRF) is performed at three time points during ileal pouch reconstruction. The intraoperative imaging findings are then analysed and correlated with the 30 day postoperative clinical outcome including occurrence of anastomotic leak of the pouch.

| 2362804 | ecrin-mdr-crc

Study about the effectiveness of localization and drainage lymph flow confirmation of colorectal cancer using near infrared light.

Project description:Interventions: Preoperative ICG local injection. Primary outcome(s): Metastatic positive rate of ICG fluorescent lymph nodes and metastatic positive rate of ICG non-fluorescent lymph nodes in regional and not regional lymph nodes. Study Design: single arm study, open(masking not used), uncontrolled control, single assignment, supportive care

| 2614978 | ecrin-mdr-crc

A multicenter, prospective clinical study on near-infrared fluorescence imaging of colorectal cancer liver metastases

Project description:Interventions: Group A:Traditional liver resection;Group B:ICG fluorescence image-guided hepatectomy Primary outcome(s): Number of liver lesions detected;1-year recurrence rate Study Design: Parallel

| 39131 | ecrin-mdr-crc

Efficacy and survival benefit of Near-Infrared Fluorescence-Guided Hepatectomy for the Detection of Colorectal Liver Metastases: A Multicenter, Prospective, Randomized Controlled Trial

Project description:Interventions: Conventional hepatectomy:Conventional hepatectomy;ICG fluorescence imaging guided hepatectomy group:ICG fluorescence imaging guided hepatectomy Primary outcome(s): 3 year overall survival rate Study Design: Parallel

| 89505 | ecrin-mdr-crc

Near-infrared-emitting nanoparticles activate collagen synthesis via TGFβ signaling

Project description:We describe the novel synthesis Ag2S nanoparticles (NPs) by using a sonochemical method and reveal the effects of NIR irradiation on the enhancement of the production of collagen through NIR-emitting Ag2S NPs. We also synthesized Li-doped Ag2S NPs that exhibited significantly increased emission intensity because of their enhanced absorption ability in the UV - NIR region.

2020-07-25 | GSE155027 | GEO

Gene expression in a 3-dimensional reconstructed human corneal epithelial tissue after near-infrared irradiation simulating solar near-infrared radiation that reaches human tissues on the Earthâs surface

Project description:To clarify the effects of near-infrared radiation, we assessed DNA microarray after water-filtered broad-spectrum near-infrared (1100-1800 nm together with a water-filter that excludes wavelengths 1400-1500 nm) irradiation. We performed 5 rounds of near-infrared irradiation (at 10 J âcm2) using 2 sets of transparent polycarbonate plates, one to block UV and the other to block both UV and near-infrared.

2016-01-05 | E-GEOD-76500 | biostudies-arrayexpress

Intraoperative identification of colonic tumor site using near infrared indocyanine green-induced endosopic fluorescence imaging system

Project description:Interventions: 0.5 ml ICG was injected the mucosa into the submucosal space of the bowel wall at just the distal side of the tumor preoperative endoscopically. We identified the colonic tumor site in the PINPOINT Endoscopic Fluorescence Imaging System, in which NIR fluorescence is superimposed in pseudo-color (green) on a white light image. Primary outcome(s): The intraoperative visibility rate of tumor site Study Design: Single arm Non-randomized

| 2636552 | ecrin-mdr-crc