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Study of αPD1-MSLN-CAR T Cells to Evaluate the Safety, Tolerability, and Effectiveness for Patients With MSLN-positive Advanced Solid Tumors

ABSTRACT: This is a single arm, open-label, dose escalation clinical study to evaluate the safety and tolerability of autologous mesothelin (MSLN)-targeted chimeric antigen receptor (MSLN-CAR) T cells secreting PD-1 nanobodies (αPD1-MSLN-CAR T cells) in patients with solid tumors.

DISEASE(S): Colorectal Cancer,Colorectal Neoplasms,Solid Tumors

PROVIDER: 2393100 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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αPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors

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