A randomised controlled trial of colorectal polyp and cancer prevention using aspirin and resistant starch in carriers of hereditary nonpolyposis colorectal cancer

ABSTRACT: Study hypothesis: 1. To study the effect of aspirin and/or resistant starch in a placebo controlled, double-blind randomised trial on carriers of Hereditary Non-Polyposis Colorectal Cancer (HNPCC) (Lynch Syndrome); 2. To assess the polyp, adenoma and/or cancer recurrence in these patients during a two to four year treatment period. Primary outcome(s): The primary endpoint will be the number, size and histological stage of colorectal carcinomas found after a minimum of 2 years treatment.

DISEASE(S): Hereditary Non-polyposis Colorectal Cancer (hnpcc)

PROVIDER: 2420467 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR