Correlation between endogenous DPD substrate concentrations and the pharmacokinetics and toxicity of 5-fluorouracil in patients with colorectal or pancreas cancer

ABSTRACT: Primary outcome(s): To determine the correlation between the baseline endogenous DPD substrate plasma ratios of DHU/U and DHT/T with the pharmacokinetics of 5-FU in patients with pancreas or colorectal cancer treated with intravenous 5-FU-based chemotherapy. Study Design: N/A: single arm study, Open (masking not used), N/A , unknown, Other

DISEASE(S): Colorectal Or Pancreas Cancer

PROVIDER: 2442076 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR