A phase II non-randomized open labeled trial for preoperative circadian chronomodulated hepatic arterial infusion (HAI) chemotherapy combined with panitumumab for liver metastases from colorectal cancer.

ABSTRACT: Interventions: Chronomodulated HAI chemotherapy group The patients of this group will receive 6 cycles of chronomodulated HAI chemotherapy with 5-FU/LV/L-OHP before hepatectomy for liver metastases from colorectal cancer Chronomodulated HAI chemotherapy with Panitumumab group The patients of this group will receive 6 cycles of chronomodulated HAI chemotherapy with 5-FU/LV/L-OHP and Panitumumab before hepatectomy for liver metastases from colorectal cancer Primary outcome(s): Response rate Study Design: Parallel Non-randomized

DISEASE(S): Liver Metastases From Colorectal Cancer

PROVIDER: 2624492 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR