Phase I/II study of preoperative treatment with capecitabine, oxaliplatin and irinotecan (XELOXIRI) in patients with advanced colorectal cancer

ABSTRACT: Interventions: Neo-adjuvant chemotherapy : XELOXIRI 6 cycles Resection : total mesorectal excision or tumor-specific mesorectal excision Adjuvant chemotherapy : XELOX 4 cycles Primary outcome(s): 1) Phase I To determine the recommended dose 2) Phase II pathological complete response rate Study Design: Single arm Non-randomized

DISEASE(S): Locally Advanced Rectal Cancer

PROVIDER: 2625365 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR