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Efficacy of traction assisted endoscopic submucosal dissection using clip and line for colorectal neoplasms: a randomized controlled trial

ABSTRACT: Interventions: Conventional ESD group Traction assisted ESD group Primary outcome(s): ESD procedure time which is measured from the start of the submucosal injection until removal of the lesion Study Design: Parallel Randomized

DISEASE(S): Colorectal Neoplasm

PROVIDER: 2633910 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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A study to evaluate the usefulness of traction-assisted endoscopic submucosal dissection using a newly developed all-in-one device used to resect colorectal polyps: a Multicenter Randomized Controlled Trial

Project description:Interventions: Procedure/Surgery : 1) onestep knife conventional ESD (control) ? Insert the colonoscope with the transparent cap attached. ? After puncturing the submucosal layer immediately around the lesion with a puncture needle for submucosal solution injection, inject the saline-based submucosal solution. ? When the lesion is sufficiently raised, submucosal dissection is performed using a dual knife. ? Retrieve the resected specimen, fix it on a styrofoam fixing plate, and ask the pathology department for tissue analysis. (2) onestep knife + Traction ESD (intermediate group) ? Insert the colonoscope with the transparent cap attached. ? After puncturing the submucosal layer immediately around the lesion with a puncture needle for submucosal solution injection, inject the saline-based submucosal solution. ? When the lesion is sufficiently raised, submucosal dissection is performed using a dual knife. ? When performing ESD, make an incision around the lesion. After fixing the rubber band to the endoscope clip from the outside of the patient, insert it into the channel of the colonoscope and fix the clip at the end of the pre-incision lesion using the clip. Using the second clip, hold the rubber band secured to the pre-fastened first clip and secure the clip in a position that will provide adequate traction. ? Implement additional ESD. ? Retrieve the resected specimen and fix it on a styrofoam fixing plate, and then ask the pathology department for tissue analysis Primary outcome(s): procedure time; resection speed Primary Purpose : Treatment, Intervention Model : Parallel, Blinding/Masking : Single, Blinding Target : Subject, Allocation : RCT

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Efficacy and Safety of Multi Loop Traction Device-assisted Colorectal Endoscopic Submucosal Dissection: A Multicenter, Randomized Clinical Trial

Project description:Interventions: 1) MLTD-ESD group Colorectal endoscopic submucosal dissection (ESD) is performed using the Multi Loop Traction Device (MLTD). The number of MLTD used in a single session is not limited. The conversion of the allocated therapeutic method is permitted. If the MLTD is ineffective for more than 10 minutes, the MLTD can be removed. 2) Conventional ESD group ESD is completed using a standard therapeutic strategy that does not involve the use of traction devices. The conversion of the allocated therapeutic method is permitted. The MLTD can be used if the endoscopist determines that the traction device has been required for more than 10 minutes. Primary outcome(s): Dissection speed (area resected [mm^2]/duration in minutes) Study Design: Parallel Randomized

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Triple-loop clip for the traction-assisted colorectal endoscopic submucosal dissection: multidirectional triple-loop traction method.

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Clinical trial of the efficacy of traction method with a band in endoscopic submucosal dissection for colorectal tumor

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Macrophages Mediate the Repair of Brain Vascular Rupture through Direct Physical Adhesion and Mechanical Traction

Project description:transcriptional profile of both macrophages and endothelial end cells between three different lesion stages (uninjured control , upon macrophage arrival , and during macrophage traction).

2016-02-23 | GSE78194 | GEO

Traction-assisted colonic endoscopic submucosal dissection using clip and line: a feasibility study.

Project description: Not available

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Macrophages Mediate the Repair of Brain Vascular Rupture through Direct Physical Adhesion and Mechanical Traction

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