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The impact of fast track model on colorectal cancer patients’ Inflammatory response and immune function after surgery

ABSTRACT: Interventions: Group A:Fast track Surgery management mode;Group B:Traditional process management mode Primary outcome(s): inflammatory mediators;Immunological indicators;postoperative rehabilitation index;Postoperative complications Study Design: Randomized parallel controlled trial

DISEASE(S): Colorectal Cancer

PROVIDER: 2675441 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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The prospective study of the impact: Fast track model on colorectal cancer patients’ quality of nutrition after surgery

Project description:Interventions: Group A:Fast track rehabilitation management mode;Group B:Traditional process management mode Primary outcome(s): Nutrition Indicators;immune indexe Study Design: Randomized parallel controlled trial

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Fast-track Perioperative Program for Laparoscopic Colorectal Surgery

Project description:Background: Laparoscopic colorectal surgery has been shown by randomized trials to be associated with better short-term clinical outcomes when compared with open surgery. However, in a traditional perioperative care setting, the reduction in hospital stay following laparoscopic surgery in these trials was modest. Fast-track perioperative programs have been introduced in the West to optimize perioperative factors to reduce the physiological/psychological stress of open colorectal surgery. However, few studies have evaluated the impact of fast-track programs on the outcomes after laparoscopic colorectal surgery. Objective: To compare the clinical and immunological outcomes of Hong Kong Chinese patients undergoing laparoscopic surgery for colorectal cancer with a "traditional" vs. a "fast-track" perioperative program. Design: Prospective randomized trial. Subjects: One hundred and twenty-eight consecutive patients undergoing elective laparoscopic resection of non-metastatic colonic and upper rectal cancer will be recruited. Interventions: Patients will be randomized to a "traditional" or a "fast-track" perioperative program. Outcome measures: Primary outcome: total postoperative hospital stay, including hospital stay of patients who are readmitted within 30 days after surgery. Secondary outcomes: immunological parameters (including systemic cytokine response and cell-mediated immune function), morbidity and mortality, quality of life, and medical costs.

| 2105727 | ecrin-mdr-crc

Evaluation of the early outcome and safety of Fast-track colorectal surgery.

Project description:Interventions: Group A:Fast-track surgery;Group B:Traditional colorectal surgery Primary outcome(s): Postoperative fluid infusion;Total cost;Postoperative hospital stay;First liquid diet after surgery;First flatus after surgery Study Design: Randomized parallel controlled trial

| 2673135 | ecrin-mdr-crc

The impact of fast track on colorectal cancer patients’ quality of life in short and medium term after surgery

Project description:Interventions: A:fast track;B:traditional process Primary outcome(s): Oncology indicators;postoperative recovery indicators;quality of life Study Design: Randomized parallel controlled trial

| 2674212 | ecrin-mdr-crc

Study Comparing Conventional and Fast Track Multi-Discipline Treatment Interventions for Colorectal Cancer

Project description:A new notion"Fast Track Multi-Discipline Treatment" for colorectal cancer is thought with several benefits such as shorter hospitalization stay and less costs. This randomized study aims to compare the differences between conventional and Fast Track Multi-Discipline Treatment for colorectal cancer in hospitalization day, complications, costs and quality of life.

| 2085833 | ecrin-mdr-crc

Fast Track Laparoscopic Surgery: A Better Option for Treating Colorectal Cancer Than Conventional Laparoscopic Surgery

Project description:To compare the outcomes of fast track laparoscopic surgery and conventional laparoscopic surgery.

| 2153679 | ecrin-mdr-crc

Evaluate the acute pain control status after surgery and influencing factors in colorectal cancer patients with Fast-Track

Project description:Interventions: FT Group:patients with Fast-Track Primary outcome(s): Postoperative recovery;the completion of FT;overall satisfaction with pain control;influencing factors of pain control;the first time of exhaust;the first time of motion after operation;hospitalization time;the amount of supplied liquid;the first time of eating after operation;the first time of drinking after operation;the time of pulling out gastric tube;the time of pulling out drainage tube;the time of pulling out urinary catheter;complications type;Houston pain outcome instrument;Social Support Rating Scale;Pain Management Index Study Design: Cross-sectional

| 2672126 | ecrin-mdr-crc

Prospective randomized control trial of fast track surgery on postoperative gastrointestinal tumor

Project description:Interventions: Regular group:Same as regular group.;Water before operation group:No lavation and nasogastric intubation. Oral intake of water 250ml 1.5-2 hours before operation; others are the same as regular group. ;Fast track group:No lavation and nasogastric intubation and oral intake of water 250ml within 1.5-2 hours before operation; place nasojejunic feeding tube during operation; other approaches same as regular group. ;Regular group:Preoperative fasting 6-8 hours, nasogastric intubation before operation; early ambulation in 24-48 hours, removing catheter at 48 hour after operation and control blood sugar under 12 mmol/l.;Glucose before operation:No lavation and nasogastric intubation. Oral 5% glucose solution 250ml within 1.5-2 hours before operation; other treatment same as regular group. ;Fast track group:Place nasojejunic feeding tube in patients with gastric cancer during operation and others are the same as regular group. Primary outcome(s): Length of hospital stay after operation Study Design: Randomized parallel controlled trial

| 2672681 | ecrin-mdr-crc

Influence of laparoscopy and/or fast-track multimodal management on gastrointestinal motility in comparison to open surgery and/or standard care

Project description:Study hypothesis: That minimal invasive laparoscopic surgery and/or multimodal patient care (fast-track) can prevent post-operative ileus and/or improve post-surgical gastrointestinal motility compared to open surgery and/or conventional patient care. Primary outcome(s): Gastrointestinal transit

| 2414686 | ecrin-mdr-crc

Fast Track Module Based Colonoscopy Training Programme for Surgical Trainees at North Jutland Surgical Departments

Project description:Specially educated trainers will be responsible for colonoscopy training of junior doctors. The educated trainers will have attended seminars held by Valori et al. The following fast track colonoscopy training program for junior doctors will consist of: 1) Endoscopy simulation training and theory course 2) supervised and partly supervised lower endoscopy. 3) Directly observed practical skills according graded by MCSAT (Mayo Clinical Skills Assessment Tool) .

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