Browse
Submit Data
Databases
API
Help

Dataset Information

7 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The effect of postoperative stellate ganglion block on myocardial injury in patients undergoing laparoscopic radical resection of colorectal cancer

ABSTRACT: Interventions: Block Group:Stellate ganglion block;Routine Group:Saline injection around the stellate ganglion Primary outcome(s): Troponin I Study Design: Parallel

DISEASE(S): Myocardial Injury After Non-cardiac Surgery

PROVIDER: 35777 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

ACCESS DATA

Json Xml

Similar Datasets

Application of rectus abdominis sheath nerve block based on surgical incision in laparoscopic radical resection of colorectal cancer

Project description:Interventions: Group A:0.4% ropivacaine 40-50ml for multi-point rectus sheath block;Group B:Multi-point rectus sheath block with 40-50ml normal saline Primary outcome(s): Pain score during rest and activity at 24 hours postoperatively Study Design: Parallel

| 2704836 | ecrin-mdr-crc

Effect of Intravenous or Perineural Dexmedetomidine and Dexamethasone for Quadratus Lumborum Block on the Quality of Recovery Following Laparoscopic Radical Colorectal Cancer Surgery

Project description:Interventions: Dexmedetomidine and dexamethasone intravenous injection group:Intravenous injection;Perineural dexmedetomidine and dexamethasone for QLB group:Compound local anesthesia to block quadratus lumborum muscle Primary outcome(s): Quality of recovery Study Design: Parallel

| 2706238 | ecrin-mdr-crc

Effect of stellate ganglion block guided by ultrasound on perioperative stress response and gastrointestinal function recovery in patients undergoing laparoscopic colorectal cancer surgery

Project description:Interventions: control group:no intervention;experimental group :stellate ganglion block with ropivacaine Primary outcome(s): norepinephrine;endothelin;cortisol;motilin;vasoactive intestinal peptide;Bowel sound recovery time;anal exhaust time;Anal defecation time Study Design: Parallel

| 2691120 | ecrin-mdr-crc

Effects of quadratus lumborum block on enhanced recovery after surgery in patients following laparoscopic radical resection of colorectal cancer

Project description:Interventions: contorl:bilateral quadratus lumborum block with 0.9 normal saline (20-30ml) on each side;QLB:bilateral quadratus lumborum block with 0.33 % ropivacaine (20-30ml) on each side Primary outcome(s): sufentanil consumption;Visual analogue pain scale (VAS) Study Design: Randomized parallel controlled trial

| 2675735 | ecrin-mdr-crc

Effects of lidocaine on the expression of rat spinal cord

Project description:This study aimed to explore the possible mechanism of lidocaine-induced neurotoxicity. A total of 40 rats were randomly assigned to 4 groups (n = 10 per group): control group; sham group, received only intrathecal catheter insertion; saline group, received an intrathecal injection of saline; and lidocaine group, received an intrathecal injection of 10% lidocaine. Neurobehavioral tests were performed on rats in each group before injection and 1, 2, 3, and 4 days after the intrathecal injection. On the fourth day, after completing neurobehavioral tests, the spinal cords of all rats from L2 to L6 were removed and immediately stored in liquid nitrogen. In the control and lidocaine groups, parts of the spinal cord tissues of three rats were selected for gene microarray analysis.Based on the results of the gene chip analysis,Five rats in each group underwent real-time quantitative polymerase chain reaction (PCR) and five Western blot analysis to verify Differentially expressed genes at the mRNA transcription and protein levels. The aim of gene chip analysis is to screen potential genes involved in lidocaine-induced neurotoxicity.

2019-09-05 | GSE136833 | GEO

Application of ultrasound-guided paraspinal block combined with lumbar quadratus block in laparoscopic radical resection of colorectal cancer

Project description:Interventions: Experimental group:Ultrasound-guided paravertebral nerve block combined with lumbar quadratus muscle block;Control group:Bilateral lumbar quadratus block guided by ultrasound Primary outcome(s): VAS score at rest and exercise at 2, 4, 6, 12, 24 and 48 hours after operation Study Design: Parallel

| 2701065 | ecrin-mdr-crc

Comparison of modified rectus sheath nerve block and transverse abdominal fascia block in laparoscopic radical resection of colorectal cancer

Project description:Interventions: Bilateral transverse abdominal fascia block combined with general anesthesia group (DTAP):Rectus abdominis sheath nerve block based on surgical incision combined with general anesthesia;Incision-based rectus sheath nerve block combined with general anesthesia group (MSRA):Rectus abdominis sheath nerve block combined with general anesthesia based on surgical incision Primary outcome(s): the dose of remifentanil Study Design: Parallel

| 2725611 | ecrin-mdr-crc

Protective effect of dexmedetomidine combined with epidural block on postoperative analgesia and early cognitive impairment in elderly patients after radical resection of colorectal cancer: a randomized controlled trial

Project description:Interventions: Dexmedetomidine group:Patients were injected with 0.6 µg/kg/h dexmedetomidine by intravenous injection after anesthesia induction to 30 min before the end of the surgery.;Epidural blockade group:The epidural blockade was conducted by epidural injection of 2% lidocaine;Combined group:Patients were treated with both dexmedetomidine and epidural blockade as described above;Control group:Patients were injected with 0.6 µg/kg/h of normal saline Primary outcome(s): MMSE scores at different time points after surgery;Ramsay scores at different time points after surgery;VAS scores at different time points after surgery;PCIA pressing times Study Design: Randomized parallel controlled trial

| 2682196 | ecrin-mdr-crc

Evaluation of pulmonary complications during laparoscopic surgery in patients with protective mechanical ventilation combined deep neuromuscular block

Project description:Interventions: Group 1:protective mechanical ventilation combined deep neuromuscular block and low pneumoperitoneum pressure ;Group 2:routine mechanical ventilation combined with routine neuromuscular block and pneumoperitoneum pressure Primary outcome(s): Neutrophil Elastase, NE;Modified Clinical Pulmonary Infection Score, mCPIS;surgical rating scale, SRS Study Design: Parallel

| 2683007 | ecrin-mdr-crc

Hippocampal gene expression signature following inflammation in epileptic mice

Project description:We used a systemic inflammatory challenge in animals with chronic mesial temporal lobe epilepsy to identify novel molecular pathways involved in seizure regulation. Mice were first rendered epileptic by a single intrahippocampal injection of kainic acid (KA). After a period of two-three weeks, mice developed spontaneous seizures and then received a single intraperitoneal injection of lipopolysaccharide (LPS) to mimic systemic inflammation, or saline as a control. Gene expression analysis by microarrays was then performed on hippocampal RNA samples extracted 4 and 24 hours after LPS or saline treatment (n=3 samples per treatment group).

2016-05-03 | GSE81024 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data