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Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer


ABSTRACT: A Phase 1/1b dose finding study to determine the OBD(s) and RP2D(s) of BMF-219, a covalent menin inhibitor small molecule, in subjects with KRAS mutated unresectable, locally advanced, or metastatic NSCLC (Cohort 1), PDAC (Cohort 2), and CRC (Cohort 3).

DISEASE(S): Stage Iii Pancreatic Cancer,Colorectal Cancer,Stage Iii Colorectal Cancer,Non Small Cell Lung Cancer,Kras Mutation-related Tumors,Stage Iv Colorectal Cancer,Stage Iv Pancreatic Cancer,Pancreatic Cancer,Lung Neoplasms,Stage Iv Non-small Cell Lung Cancer,Stage Iii Nsclc,Relapsed Cancer,Pdac,Crc,Nsclc,Stage Iv Nsclc,Refractory Cancer,Colorectal Neoplasms,Carcinoma, Non-small-cell Lung,Pancreatic Neoplasms,Stage Iii Non-small Cell Lung Cancer

PROVIDER: 919 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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