Dataset Information
DAC for study SEQCAP Analysis Of Genomic Integrity Of Disease Corrected Human Pluripotent Stem Cells
Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA144907
PROVIDER: EGAC00001000021 | EGA |
REPOSITORIES: EGA
Publications
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells.
Nature 20111012 7369
Human induced pluripotent stem cells (iPSCs) represent a unique opportunity for regenerative medicine because they offer the prospect of generating unlimited quantities of cells for autologous transplantation, with potential application in treatments for a broad range of disorders. However, the use of human iPSCs in the context of genetically inherited human disease will require the correction of disease-causing mutations in a manner that is fully compatible with clinical applications. The metho ...[more]
