Project description:RNA was extracted from normal human granulosa cells from IVF patients (hGC1 and hGC2 samples) and from adult-type ovarian granulosa cell tumor samples (H1, H8, H20, H23, H24, H28, H30, H33, H4, H18) as described in Jamieson et al, 2010. RNA from all samples was linearly amplified using the Whole Transcriptome Amplification kit (Sigma), starting from 300ng of RNA, and with 12 amplifications cycles. cDNA was purified on columns and sent to the Nimblegen platform for hybridization and transcriptional profiling. The FOXL2 locus was gentoyped in tumor samples, and all samples were found positive for the recurrent somatic mutation p.Cys134Trp which is present in >95% of adult-type ovarian granulosa cell tumors (Shah et al, 2009).

2012-08-02 | E-MTAB-483 | biostudies-arrayexpress

Data access for the 1,000 Plants (1KP) project.

Project description: Not available

| S-EPMC4306014 | biostudies-literature

Anti-VEGFA Therapy Reduces Tumor Growth and Extends Survival in a Murine Model of Ovarian Granulosa Cell Tumor.

Project description: Not available

| S-EPMC3660791 | biostudies-literature

TLR4 activates NF-?B in human ovarian granulosa tumor cells.

Project description: Not available

| S-EPMC3118942 | biostudies-literature

The 1000 Genomes Project: data management and community access.

Project description: Not available