Dataset Information
AMC Macrophage Data Access Committee
Ontology highlight
ABSTRACT:
PROVIDER: EGAC00001001123 | EGA |
REPOSITORIES: EGA
Publications
Meta-Analysis of <i>in vitro</i>-Differentiated Macrophages Identifies Transcriptomic Signatures That Classify Disease Macrophages <i>in vivo</i>.
Frontiers in immunology 20191211
Macrophages are heterogeneous leukocytes regulated in a tissue- and disease-specific context. While <i>in vitro</i> macrophage models have been used to study diseases empirically, a systematic analysis of the transcriptome thereof is lacking. Here, we acquired gene expression data from eight commonly-used <i>in vitro</i> macrophage models to perform a meta-analysis. Specifically, we obtained gene expression data from unstimulated macrophages (M0) and macrophages stimulated with lipopolysaccharid ...[more]
