Project description:This dataset was collected from viable bone marrow cells obtained at diagnosis from nine patients with high hyperdiploid ALL and one normal bone marrow sample. All samples were subjected to low pass single cell whole genome sequencing with the median sequencing coverage of 0.02x. Single nuclei in G0/G1 phase were isolated using a fluorescence-activated cell sorting (FACS) cytometer. DNA libraries were constructed and associated next-generation sequencing was carried out by European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Further details regarding the DNA libraries construction are available by Bos et. al., 2019 (https://link.springer.com/protocol/10.1007/978-1-4939-8931-7_15). The dataset has been used for copy number aberrations analysis.

| EGAS00001006347 | EGA

MethylStar: A fast and robust pre-processing pipeline for bulk or single-cell whole-genome bisulfite sequencing data.

Project description: Not available

| S-EPMC7359584 | biostudies-literature

Construction of high coverage whole-genome sequencing libraries from single colon crypts without DNA extraction or whole-genome amplification.

Project description: Not available

| S-EPMC10142246 | biostudies-literature

Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens.

Project description: Not available

| S-EPMC10155259 | biostudies-literature

Comparison of whole genome amplification techniques for human single cell exome sequencing.

Project description: Not available