Dataset Information
IBD
Ontology highlight
ABSTRACT:
PROVIDER: EGAD00000000005 | EGA |
REPOSITORIES: EGA
Publications
Actin-Interacting Amphidinolides: Syntheses and Mechanisms of Action of Amphidinolides X, J, and K.
Molecules (Basel, Switzerland) 20230706 13
Amphidinolides are a family of more than forty macrolides of varying sizes and complex structures isolated from dinoflagellates of the genus <i>Amphidinium</i>. Although all of them display potent-to-moderate cytotoxicity, their full bioactivity profile and mode of action have not been fully investigated. Access to enough material is needed for these studies, but samples of these compounds are limited due to the minute amounts that can only be obtained by either large-scale cultivation of the or ...[more]