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DATA_SET_Coverage_bias_sensitivity_of_variant_calling_for_4_WG_seq_tech - samples

ABSTRACT: DATA_SET_Coverage_bias_sensitivity_of_variant_calling_for_4_WG_seq_tech

PROVIDER: EGAD00001000174 | EGA |

REPOSITORIES: EGA

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Publications

Coverage bias and sensitivity of variant calling for four whole-genome sequencing technologies.

Rieber Nora N Zapatka Marc M Lasitschka Bärbel B Jones David D Northcott Paul P Hutter Barbara B Jäger Natalie N Kool Marcel M Taylor Michael M Lichter Peter P Pfister Stefan S Wolf Stephan S Brors Benedikt B Eils Roland R

PloS one 20130611 6

The emergence of high-throughput, next-generation sequencing technologies has dramatically altered the way we assess genomes in population genetics and in cancer genomics. Currently, there are four commonly used whole-genome sequencing platforms on the market: Illumina's HiSeq2000, Life Technologies' SOLiD 4 and its completely redesigned 5500xl SOLiD, and Complete Genomics' technology. A number of earlier studies have compared a subset of those sequencing platforms or compared those platforms wi ...[more]

PMID: 23776689

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