Genomics

Dataset Information

0

Ena-DATASET-irgb_cnr-25-06-2013-12:35:10:789-8 - samples


ABSTRACT: 1204 Sardinian males

PROVIDER: EGAD00001000618 | EGA |

REPOSITORIES: EGA

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Publications

Detection of phylogenetically informative polymorphisms in the entire euchromatic portion of human Y chromosome from a Sardinian sample.

Francalacci Paolo P   Sanna Daria D   Useli Antonella A   Berutti Riccardo R   Barbato Mario M   Whalen Michael B MB   Angius Andrea A   Sidore Carlo C   Alonso Santos S   Tofanelli Sergio S   Cucca Francesco F  

BMC research notes 20150430


<h4>Background</h4>Next-Generation Sequencing methods have led to a great increase in phylogenetically useful markers within the male specific portion of the Y chromosome, but previous studies have limited themselves to the study of the X-degenerate regions.<h4>Methods</h4>DNA was extracted from peripheral blood samples of adult males whose paternal grandfathers were born in Sardinia. The DNA samples were sequenced, genotyped and subsequently analysed for variant calling for approximately 23.1 M  ...[more]

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