Dataset Information
Cell-line Mixing Experiment Verification Data - samples
Ontology highlight
ABSTRACT:
PROVIDER: EGAD00001001044 | EGA |
REPOSITORIES: EGA
Publications
A cancer cell-line titration series for evaluating somatic classification.
BMC research notes 20151226
<h4>Background</h4>Accurate detection of somatic single nucleotide variants and small insertions and deletions from DNA sequencing experiments of tumour-normal pairs is a challenging task. Tumour samples are often contaminated with normal cells confounding the available evidence for the somatic variants. Furthermore, tumours are heterogeneous so sub-clonal variants are observed at reduced allele frequencies. We present here a cell-line titration series dataset that can be used to evaluate somati ...[more]
