Dataset Information
Ena-DATASET-GEN-GMD-02-12-2014-15:18:04:573-76 - samples
Ontology highlight
ABSTRACT:
PROVIDER: EGAD00001001086 | EGA |
REPOSITORIES: EGA
Publications
Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins.
Nature genetics 20141201 1
Understanding the genetic architecture of gene expression is an intermediate step in understanding the genetic architecture of complex diseases. RNA sequencing technologies have improved the quantification of gene expression and allow measurement of allele-specific expression (ASE). ASE is hypothesized to result from the direct effect of cis regulatory variants, but a proper estimation of the causes of ASE has not been performed thus far. In this study, we take advantage of a sample of twins to ...[more]
