Dataset Information
Ena-DATASET-ABIS-23-01-2015-20:54:00:939-774 - samples
Ontology highlight
ABSTRACT:
PROVIDER: EGAD00001001221 | EGA |
REPOSITORIES: EGA
Publications
High cortisol in 5-year-old children causes loss of DNA methylation in SINE retrotransposons: a possible role for ZNF263 in stress-related diseases.
Clinical epigenetics 20150904
<h4>Background</h4>Childhood stress leads to increased risk of many adult diseases, such as major depression and cardiovascular disease. Studies show that adults with experienced childhood stress have specific epigenetic changes, but to understand the pathways that lead to disease, we also need to study the epigenetic link prospectively in children.<h4>Results</h4>Here, we studied a homogenous group of 48 5-year-old children. By combining hair cortisol measurements (a well-documented biomarker f ...[more]