Dataset Information
Riken_ncc_rnaseq_458 - samples
Ontology highlight
ABSTRACT:
PROVIDER: EGAD00001001880 | EGA |
REPOSITORIES: EGA
Publications
Diverse modes of genomic alteration in hepatocellular carcinoma.
Genome biology 20140826 8
<h4>Background</h4>Hepatocellular carcinoma (HCC) is a heterogeneous disease with high mortality rate. Recent genomic studies have identified TP53, AXIN1, and CTNNB1 as the most frequently mutated genes. Lower frequency mutations have been reported in ARID1A, ARID2 and JAK1. In addition, hepatitis B virus (HBV) integrations into the human genome have been associated with HCC.<h4>Results</h4>Here, we deep-sequence 42 HCC patients with a combination of whole genome, exome and transcriptome sequenc ...[more]
