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Ena-DATASET-KNIH-31-07-2017-05:43:02:965-1213 - samples

ABSTRACT: A IPS03_N_ENeuron_mRNA-Seq paired end data for Early neuron cells(Tuj1)

PROVIDER: EGAD00001003490 | EGA |

REPOSITORIES: EGA

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HLA-C*05:01 and HLA-C*07:02 from 721.221 cells

Project description:HLA-C expresion varies widely across the different HLA-C alleles. MicroRNA binding can partly explain the differences in HLA-C allele expression however other contributing factors still remain undetermined. Here we use two common HLA-C alleles, HLA-C*05:01 and HLA-C*07:02, to explore differences in expression levels. Using functional, structural and peptide repertoire comparisons we demonstrate that HLA-C expression levels are not only modulated at the RNA level but also at the protein level. This dataset contains RAW data and database search results for HLA-C*05:01 and HLA-C*07:02 from the 721.221 cell line.

2017-07-03 | PXD006455 | Pride