Genomics

Dataset Information

0

E.Stieglitz_20171027_dataset_aligned - samples


ABSTRACT: Description not provided

PROVIDER: EGAD00001003794 | EGA |

REPOSITORIES: EGA

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Publications


Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative disorder of childhood caused by mutations in the Ras pathway. Outcomes in JMML vary markedly from spontaneous resolution to rapid relapse after hematopoietic stem cell transplantation. Here, we hypothesized that DNA methylation patterns would help predict disease outcome and therefore performed genome-wide DNA methylation profiling in a cohort of 39 patients. Unsupervised hierarchical clustering identifies three clusters of patients  ...[more]

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