Genomics

Dataset Information

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Ena-DATASET-STSI-01-02-2018-19:27:28:627-506 - samples

ABSTRACT: Whole-Genome Sequencing of a Healthy Aging Cohort.

PROVIDER: EGAD00001003941 | EGA |

REPOSITORIES: EGA

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Studies of long-lived individuals have revealed few genetic mechanisms for protection against age-associated disease. Therefore, we pursued genome sequencing of a related phenotype-healthy aging-to understand the genetics of disease-free aging without medical intervention. In contrast with studies of exceptional longevity, usually focused on centenarians, healthy aging is not associated with known longevity variants, but is associated with reduced genetic susceptibility to Alzheimer and coronary  ...[more]

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