Project description:Deep whole genome sequencing of sampels from the Cilento isolates. The samples are sequenced using the Illumina HiSeq X Ten system. .
This dataset contains all the data available for this study on 2019-08-19.
Project description:The aim of this study is to investigate the somatic mutations in twins with BRCA1/2 negative breast cancer with no strong family history. .
This dataset contains all the data available for this study on 2019-04-03.
Project description:We isolated T cells and monocotyes from healthy platelet donors and cultured them in resting and stimulated conditions with addition of a range of cytokines. We performed K27Ac ChM sequencing to assess the chromatin activity in different cytokines treated cells. These cellular profiles were used to map risk variants to the cytokine-induced cell states relevant for autoimmune diseases. .
This dataset contains all the data available for this study on 2019-03-19.
Project description:We will sequence at 15X coverage the genomes of 1536 IBD patients. These samples are currently onsite at Sanger and made available for sequencing via our collaboration with the UK IBD Genetics consortium.
This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/ .
This dataset contains all the data available for this study on 2019-04-01.
Project description:Drug resistant population of PC9(human non-small cell lung cancer) or A375 (human melanoma) cell lines were used for this study. By exome sequencing, we will analyse mutations of cells in drug tolerent state and after drug holiday. .
This dataset contains all the data available for this study on 2019-04-03.
Project description:We will use targeted exome sequencing to examine normal appearing epithelium and whole exome and whole genome sequencing of microdissected clones identified by immunostaining
Some of the samples will be of low DNA concentration and therefore may require extra rounds of amplification during library prep.
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This dataset contains all the data available for this study on 2019-04-03.