Genomics

Dataset Information

0

61f6508f-ab66-4d36-ad86-028a0ff97746 - samples


ABSTRACT: The whole exome sequencing data of 291 tumor/normal samples from 121 cHCC-ICC cases.

PROVIDER: EGAD00001005183 | EGA |

REPOSITORIES: EGA

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Publications


We performed genomic and transcriptomic sequencing of 133 combined hepatocellular and intrahepatic cholangiocarcinoma (cHCC-ICC) cases, including separate, combined, and mixed subtypes. Integrative comparison of cHCC-ICC with hepatocellular carcinoma and intrahepatic cholangiocarcinoma revealed that combined and mixed type cHCC-ICCs are distinct subtypes with different clinical and molecular features. Integrating laser microdissection, cancer cell fraction analysis, and single nucleus sequencing  ...[more]

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