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Ena-DATASET-KNIH-30-03-2021-02:36:09:338-364 - samples

ABSTRACT: ADMSC05 h3k4me3 ChIP-Seq paired end data

PROVIDER: EGAD00001007378 | EGA |

REPOSITORIES: EGA

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ena-DATASET-KNIH-30-03-2021-02:36:45:403-365 - samples

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S. fradiae WT and KOS155-3C R5/No Glucose 02/09/03

Project description:RNA timecourse data for Streptomyces fradiae wildtype (ATCC19609) and overproducing strain KOS155-3C(RUS). Strains were grown at 30 C in shake flask cultures in R5 medium with no glucose. RNA samples were harvested over 5 days as tylosin was produced. 12 h RNA samples of each strain were used as the reference sample(green) within their respective timecourses. The WT gDNA vs. 12 h RNA control displays relative gene expression at the beginning of the timecourse. The 12 h RNA control compares initial RNA levels between the WT and overproducer. Groups of assays that are related as part of a time series. Keywords: time_series_design

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S. fradiae WT and KOS155-3C R5/No Glucose 02/09/03

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ena-DATASET-KNIH-30-03-2021-02:35:40:213-363 - samples

Project description:ADMSC05 h3k4me1 ChIP-Seq paired end data

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ena-DATASET-KNIH-30-03-2021-02:34:38:503-361 - samples

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ena-DATASET-KNIH-30-03-2021-02:35:05:456-362 - samples

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Surveillance of Acute SARS-CoV-2 Infections in Elementary Schools and Daycare Facilities in Bavaria, Germany (09/2020-03/2021).

Project description:IntroductionHere we report our results of a multi-center, open cohort study ("COVID-Kids-Bavaria") investigating the distribution of acute SARS-CoV-2 infections among children and staff in 99 daycare facilities and 48 elementary schools in Bavaria, Germany.Materials and methodsOverall, 2,568 children (1,337 school children, 1,231 preschool children) and 1,288 adults (466 teachers, 822 daycare staff) consented to participate in the study and were randomly tested in three consecutive phases (September/October 2020, November/December 2020, March 2021). In total, 7,062 throat swabs were analyzed for SARS-CoV-2 by commercial RT-PCR kits.ResultsIn phase I, only one daycare worker tested positive. In phase II, SARS-CoV-2 was detected in three daycare workers, two preschool children, and seven school children. In phase III, no sample tested positive. This corresponds to a positive test rate of 0.05% in phase I, 0.4% in phase II and 0% in phase III. Correlation of a positive PCR test result with the local-7-day incidence values showed a strong association of a 7-day-incidence of more than 100/100,000 as compared to <100/100,000 (OR = 10.3 [1.5-438], p < 0.005). After phase III, antibody testing was offered to 713 study participants in elementary schools. A seroprevalence rate of 7.7% (students) and 4.5% (teachers) was determined.DiscussionDuring the initial waves of the SARS-CoV-2 pandemic, the risk of a positive SARS-CoV-2 result correlated positively with the local 7-day incidence. Hence, the occurrence of SARS-CoV-2 infections were reflected in schools and daycare facilities. An increased risk of SARS-CoV-2 transmission in the setting of daycare and elementary schooling was unlikely.

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Project description:Pancreas-Islet06 h3k4me3 ChIP-Seq paired end data

| EGAD00001007454 | EGA