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Ena-DATASET-BCCA-11-05-2021-16:26:34:920-117 - samples

ABSTRACT: Follicular lymphoma (FL) is an indolent cancer of mature B-cells but carries increased risk of transformation to a more aggressive histology over time. We present here comprehensive profiling both tumor and immune compartments in 6 diagnostic FL biopsies by single-cell RNA sequencing. This confirmed results from 155 FL tumors characterized by mass cytometry (CyTOF) which revealed two distinct evolutionary trajectories with disparate risk of transformation and alternate biologies.

PROVIDER: EGAD00001007691 | EGA |

REPOSITORIES: EGA

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