Genomics

Dataset Information

0

Ena-DATASET-ErasmusMC-30-07-2021-13:54:47:012-763 - samples


ABSTRACT: Intellance-2: rRNA-minus RNA-seq

PROVIDER: EGAD00001007943 | EGA |

REPOSITORIES: EGA

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Publications


<h4>Background</h4>The randomized phase II INTELLANCE-2/EORTC_1410 trial on EGFR-amplified recurrent glioblastomas showed a trend towards improved overall survival when patients were treated with depatux-m plus temozolomide compared with the control arm of alkylating chemotherapy only. We here performed translational research on material derived from this clinical trial to identify patients that benefit from this treatment.<h4>Methods</h4>Targeted DNA-sequencing and whole transcriptome analysis  ...[more]

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