Genomics

Dataset Information

0

MDC-LSR-SAHLSIS-control - samples


ABSTRACT: Controls

PROVIDER: EGAD00010000620 | EGA |

REPOSITORIES: EGA

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Publications

A genetic risk score for hypertension associates with the risk of ischemic stroke in a Swedish case-control study.

Fava Cristiano C   Sjögren Marketa M   Olsson Sandra S   Lövkvist Håkan H   Jood Katarina K   Engström Gunnar G   Hedblad Bo B   Norrving Bo B   Jern Christina C   Lindgren Arne A   Melander Olle O  

European journal of human genetics : EJHG 20141008 7


Genetic risk scores (GRS), summing up the total effect of several single-nucleotide polymorphisms (SNPs) in genes associated with either coronary risk or cardiovascular risk factors, have been tested for association with ischemic stroke with conflicting results. Recently an association was found between a GRS based on 29 SNPs discovered by genome-wide association studies and hypertension. The aim of our study was to investigate the possible association of the same GRS with ischemic stroke on top  ...[more]

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