Dataset Information
Glioma_Exome_GER_CASES - samples
Ontology highlight
ABSTRACT:
PROVIDER: EGAD00010000752 | EGA |
REPOSITORIES: EGA
Publications
Search for new loci and low-frequency variants influencing glioma risk by exome-array analysis.
European journal of human genetics : EJHG 20150812 5
To identify protein-altering variants (PAVs) for glioma, we analysed Illumina HumanExome BeadChip exome-array data on 1882 glioma cases and 8079 controls from three independent European populations. In addition to single-variant tests we incorporated information on the predicted functional consequences of PAVs and analysed sets of genes with a higher likelihood of having a role in glioma on the basis of the profile of somatic mutations documented by large-scale sequencing initiatives. Globally t ...[more]
