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OvCan2

ABSTRACT: Digital images of ovarian cancer metastases

PROVIDER: EGAD00010001099 | EGA |

REPOSITORIES: EGA

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Similarity and diversity of the tumor microenvironment in multiple metastases: critical implications for overall and progression-free survival of high-grade serous ovarian cancer.

Heindl Andreas A Lan Chunyan C Rodrigues Daniel Nava DN Koelble Konrad K Yuan Yinyin Y

Oncotarget 20161101 44

The tumor microenvironment is pivotal in influencing cancer progression and metastasis. Different cells co-exist with high spatial diversity within a patient, yet their combinatorial effects are poorly understood. We investigate the similarity of the tumor microenvironment of 192 local metastatic lesions in 61 ovarian cancer patients. An ecologically inspired measure of microenvironmental diversity derived from multiple metastasis sites is correlated with clinicopathological characteristics and ...[more]

PMID: 27661102

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